Pet Immune-Mediated Diseases

For many different illnesses and infections, a robust and functional immune system is required. The immune system in healthy dogs and cats is in charge of identifying foreign cells like bacteria or fungi and then eliminating them from the body.

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Immune-Mediated Diseases

Immune-mediated skin diseases occur when the body’s immune system mistakenly attacks its own tissues, leading to skin inflammation, damage, and other related symptoms. These conditions can affect both dogs and cats, with clinical signs ranging from skin lesions and hair loss to severe ulceration. Common immune-mediated dermatological diseases include pemphigus complex (e.g., pemphigus foliaceus), where the immune system targets skin cells, causing blistering and crusting, and systemic lupus erythematosus (SLE), which can lead to skin rashes, ulcers, and other systemic symptoms. Canine discoid lupus erythematosus (DLE) primarily affects the nose, causing depigmentation, crusting, and ulceration. Another common condition is autoimmune thyroiditis, which can result in alopecia and changes in the coat and skin quality. Treatment often involves immunosuppressive medications, such as corticosteroids, and supportive care to manage symptoms and prevent flare-ups. Early diagnosis and appropriate therapy are crucial to controlling these conditions and improving the pet’s quality of life.